Products for Research Use Only
RegisterLogin

FAPI-34

CAT: 0804-HY-139401-02Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-139401-02Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
FAPI-34 is a fibroblast-activating protein (FAP) inhibitor with favorable pharmacokinetic and biochemical properties. (patent WO2019154886A1) .
CAS Number
2374782-07-5
UNSPSC
12352005
Target
FAP
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fapi-34.html
Purity
99.67
Solubility
DMSO : 160 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC=NC(C=C2)=C1C=C2OCCCN(CC3)CCN3C(CN(CC4=NC=CN4CC(N[C@H](C(O)=O)CC(C(O)=O)C(O)=O)=O)CC5=NC=CN5CC(N[C@H](C(O)=O)CC(C(O)=O)C(O)=O)=O)=O)NCC(N(CC6(F)F)[C@@H](C6)C#N)=O
Molecular Formula
C50H57F2N13O18
Molecular Weight
1166.06
References & Citations
[1]Uwe Haberkorn, et al. Fap inhibitor. WO2019154886A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

CID 156060696
CAS Number2374782-07-5
PubChem CID156060696
IUPAC Name(3S)-3-[[2-[2-[[[2-[4-[3-[4-[[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]carbamoyl]quinolin-6-yl]oxypropyl]piperazin-1-yl]-2-oxoethyl]-[[1-[2-oxo-2-[[(1S)-1,3,3-tricarboxypropyl]amino]ethyl]imidazol-2-yl]methyl]amino]methyl]imidazol-1-yl]acetyl]amino]propane-1,1,3-tricarboxylic acid
Molecular FormulaC50H57F2N13O18
Molecular Weight1166.1
XLogP-6.5
Topological Polar Surface Area440
Hydrogen Bond Donor Count9
Hydrogen Bond Acceptor Count26
Rotatable Bond Count30
Heavy Atom Count83
Formal Charge0
Complexity2330
SMILES
C1CN(CCN1CCCOC2=CC3=C(C=CN=C3C=C2)C(=O)NCC(=O)N4CC(C[C@H]4C#N)(F)F)C(=O)CN(CC5=NC=CN5CC(=O)N[C@@H](CC(C(=O)O)C(=O)O)C(=O)O)CC6=NC=CN6CC(=O)N[C@@H](CC(C(=O)O)C(=O)O)C(=O)O
InChI
InChI=1S/C50H57F2N13O18/c51-50(52)19-28(20-53)65(27-50)41(68)21-57-43(70)30-4-5-54-34-3-2-29(16-31(30)34)83-15-1-8-60-11-13-62(14-12-60)42(69)26-61(22-37-55-6-9-63(37)24-39(66)58-35(48(79)80)17-32(44(71)72)45(73)74)23-38-56-7-10-64(38)25-40(67)59-36(49(81)82)18-33(46(75)76)47(77)78/h2-7,9-10,16,28,32-33,35-36H,1,8,11-15,17-19,21-27H2,(H,57,70)(H,58,66)(H,59,67)(H,71,72)(H,73,74)(H,75,76)(H,77,78)(H,79,80)(H,81,82)/t28-,35-,36-/m0/s1
InChIKey
FPOZMWSPTRNDPQ-UVXHQIPUSA-N
Chemical Structure
2D Structure
2D structure of CID 156060696
CAS: 2374782-07-5
CID: 156060696
Formula: C50H57F2N13O18
MW: 1166.1
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight1166.1
XLogP3-6.5
Hydrogen Bond Donor Count9
Hydrogen Bond Acceptor Count26
Rotatable Bond Count30
Exact Mass1165.39125834
Monoisotopic Mass1165.39125834
Topological Polar Surface Area440 Ų
Heavy Atom Count83
Formal Charge0
Complexity2330
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-128643-01FAPI-4
HY-136641-01NOTA-FAPI
HY-137331-01FAPI-46
HY-164725-01FAPI-mFS
HY-175322FAPI-P8PN
HY-177435-01FAPI-800CW
HY-147173-01FAPI-74
HY-128642-01FAPI-2
HY-174421FAPI-JNU
HY-164316-01FT-FAPI-12_9

Alternative Products

CatalogName
MBS5802472FAPI-34
408013FAPI-4
MBS5820330FAPI-74
BA5958-1FAPI-46
T11263-01FAPI-2
GTR19264464-01FAPI-P8PN
T211034-01FAPI-JNU
GTR19236716NOTA-FAPI
GTR19274534-01FAPI-800CW

Popular Products