Exatecan-methylacetamide-OH

• UNSPSC Description:

  Exatecan-methylacetamide-OH (compound 6) is a Exatecan derivative with anticancer effects. Exatecan-methylacetamide-OH is an ADC cytotoxin that can be used to synthesize Antibody-Drug Conjugates (ADCs) (CN112125915A; compound 6)[1].

• Target Antigen:

  ADC Cytotoxin; Topoisomerase

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/exatecan-methylacetamide-oh.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  OCC(N([C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62)C)=O

• Molecular Weight:

  507.51

• References & Citations:

  [1]Yi Zhu, et al. Camptothecin derivative and conjugate thereof. CN112125915A.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported

• CAS Number:

  2594423-51-3