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Exatecan-methylacetamide-OH

CAT: 0804-HY-156849-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-156849-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Exatecan-methylacetamide-OH (compound 6) is a Exatecan derivative with anticancer effects. Exatecan-methylacetamide-OH is an ADC cytotoxin that can be used to synthesize Antibody-Drug Conjugates (ADCs) (CN112125915A; compound 6) [1].
CAS Number
2594423-51-3
UNSPSC
12352203
Target
ADC Payload; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/exatecan-methylacetamide-oh.html
Purity
97.30
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCC(N([C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62)C)=O
Molecular Formula
C27H26FN3O6
Molecular Weight
507.51
References & Citations
[1]Yi Zhu, et al. Camptothecin derivative and conjugate thereof. CN112125915A.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Camptothecins

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