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(1-OH) -Exatecan

CAT: 0804-HY-156642Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156642Size:1 Each
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Description
(1-OH) -Exatecan is a quinoline ring compound. (1-OH) -Exatecan has substantial antiproliferative effects. (1-OH) -Exatecan can be used for cancer diseases research[1].
CAS Number
2894780-53-9
UNSPSC
12352005
Target
ADC Payload; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-oh-exatecan.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62
Molecular Formula
C24H21FN2O5
Molecular Weight
436.43
References & Citations
[1]Sharma S, et al. Tailored Quinolines Demonstrate Flexibility to Exert Antitumor Effects through Varied Mechanisms-A Medicinal Perspective. Anticancer Agents Med Chem. 2021;21 (3) :288-315.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Camptothecins

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