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BMS-707035

CAT: 0804-HY-13269-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13269-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS-707035 is a potent orally active HIV-1 integrase strand transfer inhibitor (INSTI) . BMS-707035 has enzyme inhibitory with an IC50 value of 3 nM. BMS-707035 also has weak CYP inhibiton and antiviral activity. BMS-707035 can be used for the research of human immunodeficiency virus-1 (HIV-1) [1].
CAS Number
729607-74-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HIV; HIV Integrase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/BMS-707035.html
Purity
99.99
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
FC1=CC=C(C=C1)CNC(C(N=C(N2C)N3S(CCCC3)(=O)=O)=C(C2=O)O)=O
Molecular Formula
C17H19FN4O5S
Molecular Weight
410.42
Precautions
H302, H315, H319, H335
References & Citations
[1]B Narasimhulu Naidu, et al. The discovery and preclinical evaluation of BMS-707035, a potent HIV-1 integrase strand transfer inhibitor. Bioorg Med Chem Lett. 2018 Jul 1;28 (12) :2124-2130.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1

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