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L-5-Hydroxytryptophan

CAT: 0804-HY-B1716-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1716-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist[1]. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia[2][3][4][5].
CAS Number
4350-09-8
Product Name Alternative
L-5-HTP; Oxitriptan
UNSPSC
12352005
Hazard Statement
H301
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/L-5-Hydroxytryptophan.html
Purity
99.99
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 14 mg/mL (ultrasonic)
Smiles
N[C@@H](CC1=CNC2=CC=C(O)C=C12)C(O)=O
Molecular Formula
C11H12N2O3
Molecular Weight
220.23
Precautions
H301
References & Citations
[1]ARVID CARLSSON, et al. 3,4-Dihydroxyphenylalanine and 5-Hydroxytryptophan as Reserpine Antagonists. Nature 180, page1200 (1957) .|[2]Caruso I, et al. Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. J Int Med Res. 1990 May-Jun;18 (3) :201-9.|[3]Thal LJ, et al. Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations. Ann Neurol. 1980 Jun;7 (6) :570-6.|[4]Boiardi A, et al. 5-OH-Tryptophane in migraine: clinical and neurophysiological considerations. J Neurol. 1981;225 (1) :41-6.|[5]Trouillas P, et al. Improvement of cerebellar ataxia with levorotatory form of 5-hydroxytryptophan. A double-blind study with quantified data processing. Arch Neurol. 1988 Nov;45 (11) :1217-22.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite

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