5-Hydroxytryptophan
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- Dry Ice Shipment: No


5-Hydroxytryptophan
UNSPSC Description:
5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. [1][2][3].Target Antigen:
Endogenous MetaboliteType:
Natural ProductsRelated Pathways:
Metabolic Enzyme/ProteaseApplications:
Metabolism-protein/nucleotide metabolismField of Research:
Metabolic DiseaseAssay Protocol:
https://www.medchemexpress.com/5-hydroxytryptophan.htmlPurity:
99.92Solubility:
DMSO : 83.33 mg/mL (ultrasonic)|H2O : 12.5 mg/mL (ultrasonic)Smiles:
NC(CC1=CNC2=CC=C(O)C=C12)C(O)=OMolecular Weight:
220.228References & Citations:
[1]Gartside SE, et al. Mediation of ACTH and prolactin responses to 5-HTP by 5-HT2 receptors. Eur J Pharmacol. 1990 Apr 10;179(1-2):103-9.|[2]Gijsman HJ, et al. Placebo-controlled comparison of three dose-regimens of 5-hydroxytryptophan challenge test in healthy volunteers. J Clin Psychopharmacol. 2002 Apr;22(2):183-9.|[3]Schruers K, et al. Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients. Psychiatry Res. 2002 Dec 30;113(3):237-43.Shipping Conditions:
Room TemperatureStorage Conditions:
-20°C, 3 years; 4°C, 2 years (Powder)Clinical Information:
LaunchedCAS Number:
56-69-9
