5-Hydroxytryptophan

• Description:

  5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. [1][2][3].

• Product Name Alternative:

  5-HTP; DL-5-Hydroxytryptophan

• UNSPSC:

  12352005

• Hazard Statement:

  H301

• Target:

  5-HT Receptor; Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/5-hydroxytryptophan.html

• Purity:

  99.92

• Solubility:

  DMSO : 83.33 mg/mL (ultrasonic) |H2O : 12.5 mg/mL (ultrasonic)

• Smiles:

  NC(CC1=CNC2=CC=C(O)C=C12)C(O)=O

• Molecular Formula:

  C11H12N2O3

• Molecular Weight:

  220.23

• Precautions:

  H301

• References & Citations:

  [1]Gartside SE, et al. Mediation of ACTH and prolactin responses to 5-HTP by 5-HT2 receptors. Eur J Pharmacol. 1990 Apr 10;179 (1-2) :103-9.|[2]Gijsman HJ, et al. Placebo-controlled comparison of three dose-regimens of 5-hydroxytryptophan challenge test in healthy volunteers. J Clin Psychopharmacol. 2002 Apr;22 (2) :183-9.|[3]Schruers K, et al. Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients. Psychiatry Res. 2002 Dec 30;113 (3) :237-43.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  Launched

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  [56-69-9]