5-Hydroxytryptophol

CAT: 0804-HY-W041019-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W041019-01Size:5 mg
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Description
5-Hydroxytryptophol is a mammalian serotonin metabolite that can be used as a sensitive biomarker for recent alcohol intake. 5-Hydroxytryptophol is formed by alcohol-induced changes in the serotonin metabolic pathway and is excreted in the urine as a glucuronic acid conjugate. 5-Hydroxytryptophol is elevated in urine excretion and can be used clinically to monitor alcohol intake in scenarios such as alcohol relapse[1][2].
CAS Number
[154-02-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/3-_2-Hydroxyethyl_-1H-indol-5-ol.html
Purity
99.13
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
OC1=CC2=C(NC=C2CCO)C=C1
Molecular Formula
C10H11NO2
Molecular Weight
177.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Beck O, et al. 5-hydroxytryptophol as a marker for recent alcohol intake. Addiction. 2003 Dec;98 Suppl 2:63-72.|[2]Eccleston D, et al. The formation of 5-hydroxytryptophol in brain in vitro. Br J Pharmacol Chemother. 1966 Dec;28 (3) :367-77.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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