PDGFRα/β/VEGFR-2-IN-1

• UNSPSC Description:

  PDGFRα/β/VEGFR-2-IN-1 (6f), a multiple PDGFRα/ß and VEGFR-2 tyrosine kinase inhibitor, particularly targets PDGFRα, PDGFRβ, and VEGFR-2 kinases with Nano molar concentrations[1].

• Target Antigen:

  PDGFR; VEGFR

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pdgfrα-β-vegfr-2-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  BrC1=CC=C(NC(COC2=CC=C(/C=C3C(NC4=C\3C=C(Cl)C=C4)=O)C=C2)=O)C=C1

• Molecular Weight:

  483.74

• References & Citations:

  [1]Hend A A Ezelarab, et al. New 2-oxoindole derivatives as multiple PDGFRα/ß and VEGFR-2 tyrosine kinase inhibitors. Bioorg Chem. 2024 Apr:145:107234.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported