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ZW4864 free base

CAT: 0931-T9642-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9642-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2632259-92-6
Target
Wnt/beta-catenin
Related Pathways
Stem Cells, Cytoskeletal Signaling
Purity
0.9981
Bioactivity
ZW4864 (free base) is an orally active and selective β-catenin/B-Cell lymphoma 9 protein-protein interaction (β-catenin/BCL9 PPI) inhibitor, with a K_i value of 0.76 μM and an IC_50 value of 0.87 μM [1]. ZW4864 (free base) also demonstrates good pharmacokinetic properties.
Smiles
CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1
Molecular Formula
C33H42N6O3
Molecular Weight
570.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C