Thalidomide-O-PEG1-OH

• Target:

  PROTAC Linker

• Related Pathways:

  PROTAC

• Bioactivity:

  Thalidomide-O-PEG1-OH is a PROTAC linker characterized by its combination of Thalidomide with O-ethyl. Thalidomide acts as a ligand for the E3 ubiquitin ligase, leading to protein ubiquitination and subsequent proteasomal degradation. Additionally, the hydroxy group serves as a versatile handle, facilitating the formation of more complex structures through various reactions.

• Smiles:

  O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCO)C3C2=O)CC1

• Molecular Formula:

  C15H14N2O6

• Molecular Weight:

  318.281

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2416234-31-4