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Thalidomide-O-PEG1-OH

CAT: 0931-T206600-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T206600-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2416234-31-4
Target
PROTAC Linker
Related Pathways
PROTAC
Bioactivity
Thalidomide-O-PEG1-OH is a PROTAC linker characterized by its combination of Thalidomide with O-ethyl. Thalidomide acts as a ligand for the E3 ubiquitin ligase, leading to protein ubiquitination and subsequent proteasomal degradation. Additionally, the hydroxy group serves as a versatile handle, facilitating the formation of more complex structures through various reactions.
Smiles
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCO)C3C2=O)CC1
Molecular Formula
C15H14N2O6
Molecular Weight
318.281
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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