Thalidomide-O-PEG1-OH

• Target :

  PROTAC Linker

• Related Pathways :

  PROTAC

• Bioactivity :

  Thalidomide-O-PEG1-OH is a PROTAC linker characterized by its combination of Thalidomide with O-ethyl. Thalidomide acts as a ligand for the E3 ubiquitin ligase, leading to protein ubiquitination and subsequent proteasomal degradation. Additionally, the hydroxy group serves as a versatile handle, facilitating the formation of more complex structures through various reactions.

• Smiles :

  O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCO)C3C2=O)CC1

• Molecular Formula :

  C15H14N2O6

• Molecular Weight :

  318.281

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2416234-31-4