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Thalidomide-4-OH-C11-OH

CAT: 0931-T207724-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207724-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3071165-50-6
Target
E3 Ligase Ligand-Linker Conjugate
Related Pathways
PROTAC
Bioactivity
Thalidomide-4-OH-C11-OH is a conjugate of an E3 ligase ligand and a linker (E3LigaseLigand-Linker Conjugates), comprising Thalidomide-4-OH and the corresponding linker. Thalidomide-4-OH-C11-OH acts as a Cereblon ligand to recruit CRBN protein and serves as a key intermediate for synthesizing complete PROTAC molecules, such as PROTAC GPX4 degrader-4.
Smiles
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCCCCCCCCCCO)C3C2=O)CC1
Molecular Formula
C24H32N2O6
Molecular Weight
444.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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