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Thalidomide-5-OH (Standard)

CAT: 0804-HY-23095R-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-23095R-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thalidomide-5-OH (Standard) is the analytical standard of Thalidomide-5-OH. This product is intended for research and analytical applications. Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTACs[1].
CAS Number
64567-60-8
UNSPSC
12352100
Target
Apoptosis; Autophagy; Ligands for E3 Ligase; Reference Standards
Related Pathways
Apoptosis; Autophagy; Others; PROTAC
Field of Research
Cancer
Smiles
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(O)=C3)=O
Molecular Formula
C13H10N2O5
Molecular Weight
274.23
References & Citations
[1]Megan G Marks, et al. Effects of Putative Hydroxylated Thalidomide Metabolites on Blood Vessel Density in the Chorioallantoic Membrane (CAM) Assay and on Tumor and Endothelial Cell Proliferation. Biol Pharm Bull. 2002 May;25 (5) :597-604.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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