Thalidomide 5-fluoride

• Target:

  Autophagy|||Ligand for E3 Ligase|||Apoptosis

• Related Pathways:

  PROTAC|||Autophagy|||Apoptosis

• Purity:

  0.9862

• Bioactivity:

  Thalidomide 5-fluoride (H-Isoindole-1,3 (2H) -dione, 2- (2,6-dioxo-3-piperidinyl) -5-fluoro-) is a thalidomide-based Cereblon ligand that binds to the IRAK4 protein ligand via a linker to form PROTACIRAK4 degrader-1.

• Smiles:

  O=C1N(C(=O)C=2C1=CC(F)=CC2)C3C(=O)NC(=O)CC3

• Molecular Formula:

  C13H9FN2O4

• Molecular Weight:

  276.22

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  835616-61-0