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Tyk2-IN-16

CAT: 0931-T87585-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T87585-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3010874-30-0
Target
JAK
Related Pathways
Stem Cells, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Chromatin/Epigenetic, Angiogenesis
Bioactivity
Tyk2-IN-16 is a potent and selective TYK2 inhibitor with an IC50 of less than 10 nM for TYK2-JH2. It inhibits pSTAT4 in NK92 cells with an IC50 of under 10 nM (WO2023220046A1; compound 184) [1].
Smiles
N(C(C)=O)C=1C=C2C(C(=NN2C=3N=C(C(C)(F)F)C=CN3)N4CC(C#N)(C)CC4)=CN1
Molecular Formula
C20H20F2N8O
Molecular Weight
426.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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