Antitumor agent-78

• Target :

  Others|||COX|||Apoptosis|||Bcl-2 Family|||Ferroptosis

• Related Pathways :

  Immunology/Inflammation|||Apoptosis|||Neuroscience|||Others

• Bioactivity :

  Antitumor agent-78 inhibits GPx-4 and elevates COX2, leading to ferroptosis. antitumor agent-78 activates the tumor cell intrinsic apoptotic pathway (Bax-Bcl-2-caspase-3) and inhibits the epithelial mesenchymal transition (EMT) process in tumor cells. Antitumor agent-78 exhibits antitumor effects and inhibits the growth and migration of cancer cells.

• Smiles :

  [Pt++].[NH-][C@@H]1CCCC[C@H]1[NH-].OC(=O)C1(CC(O)(C1)C(F)(F)F)C(O)=O

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  9007-83-4