HDAC-IN-45

• Target :

  Others|||HDAC

• Related Pathways :

  Others|||DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Bioactivity :

  HDAC-IN -45, a small molecule HDAC inhibitor, was able to form hydrogen bonds with Y303 residues and exhibited anticancer effects. HDAC-IN-45 significantly inhibited HDAC1, HDAC2 and HDAC3 subtypes with their IC50 values of 0.108, 0.585 and 0.563 ?M, respectively.

• Smiles :

  C(N1C=2C(=C(NC3=CC(Cl)=C(F)C=C3)N=C(N)N2)N=C1)C4=CC=C(C(NC5=C(N)C=CC=C5)=O)C=C4

• Molecular Formula :

  C25H20ClFN8O

• Molecular Weight :

  502.93

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2421122-61-2