HDAC-IN-39

• Target:

  HDAC|||Microtubule Associated|||Others|||Apoptosis

• Related Pathways:

  Chromatin/Epigenetic|||Others|||DNA Damage/DNA Repair|||Cytoskeletal Signaling|||Apoptosis

• Bioactivity:

  HDAC-IN-39 is a potent inhibitor of HDAC and is able to act on HDAC1, HDAC2 and HDAC3 with IC50 values of 1.07 ?M, 1.47 ?M and 2.27 ?M, respectively. HDAC-IN-39 induces cell cycle arrest in G2/M phase and also significantly inhibits microtubule polymerization. HDAC-IN-39 exhibits good anticancer effects on HDAC-IN-39 exhibited good anti-cancer effects on drug-resistant cancer cells.

• Smiles:

  N(S(=O)(=O)C1=CC=C(OC)C=C1)C2=C(NCC3=CC=C(C(NC4=C(N)C=CC=C4)=O)C=C3)C=CC=C2

• Molecular Formula:

  C27H26N4O4S

• Molecular Weight:

  502.58

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2414046-33-4