HDAC-IN-39

CAT: 0931-T63416-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T63416-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2414046-33-4
Target
HDAC|||Microtubule Associated|||Others|||Apoptosis
Related Pathways
Chromatin/Epigenetic|||Others|||DNA Damage/DNA Repair|||Cytoskeletal Signaling|||Apoptosis
Bioactivity
HDAC-IN-39 is a potent inhibitor of HDAC and is able to act on HDAC1, HDAC2 and HDAC3 with IC50 values of 1.07 ?M, 1.47 ?M and 2.27 ?M, respectively. HDAC-IN-39 induces cell cycle arrest in G2/M phase and also significantly inhibits microtubule polymerization. HDAC-IN-39 exhibits good anticancer effects on HDAC-IN-39 exhibited good anti-cancer effects on drug-resistant cancer cells.
Smiles
N(S(=O)(=O)C1=CC=C(OC)C=C1)C2=C(NCC3=CC=C(C(NC4=C(N)C=CC=C4)=O)C=C3)C=CC=C2
Molecular Formula
C27H26N4O4S
Molecular Weight
502.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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