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HCAIX-IN-12

CAT: 0931-T61896-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61896-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2414598-85-7
Target
Carbonic Anhydrase, Reactive Oxygen Species, Apoptosis, Others
Related Pathways
NF-κB, Others, Apoptosis, Metabolism, Immunology/Inflammation
Bioactivity
HCAIX-IN-12 is an effective hCAIX inhibitor, IC50 for CAIX and CAII is 0.74 and 10.78 μM , respectively. hCAIX-IN-12 inhibits cell proliferation and induces apoptosis. HCAIX-IN-12 can increase the generation of ROS. HCAIX-IN-12 has research potential in colorectal cancer (CRC) .
Smiles
N(S(=O)(=O)C1=CC=C(N)C=C1)C2=C(SC=C2)C3=NC(=NO3)C4=CC=CC=C4
Molecular Formula
C18H14N4O3S2
Molecular Weight
398.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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