GA-017

• Target :

  Others|||YAP

• Related Pathways :

  Stem Cells|||Others

• Purity :

  0.9938

• Bioactivity :

  GA-017 is a potent, selective inhibitor of LATS1 and LATS2 (large tumor suppressor kinase 1/2), exhibiting IC50 values of 4.10 and 3.92 nM, respectively. This compound simultaneously acts as an activator of cell proliferation by promoting YAP/TAZ activation and their nuclear translocation. Additionally, GA-017 enhances cell growth in 3D culture conditions and augments the ex vivo formation of mouse intestinal organoids [1].

• Smiles :

  CC\C(=N\NC(=O)NCc1cccc(O)c1)c1ccc(O)c(C)c1O

• Molecular Formula :

  C18H21N3O4

• Molecular Weight :

  343.38

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2351906-74-4