GA 0113

CAT: 0931-MF-0142816-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0142816-01Size:100 mg
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CAS Number
200639-61-8
Target
RAAS
Related Pathways
Endocrinology/Hormones
Bioactivity
GA 0113 is an effective orally active antagonist of the angiotensin II (Ang II) AT1 receptor. It inhibits the hypertensive response induced by Ang II, with an ID50 of 0.032 mg/kg, and dose-dependently increases plasma renin activity for up to 48 hours.
Smiles
O=S(=O)(NC=1C=CC=CC1C2=NC=3C=CC(=CC3C=C2)CN4C5=NC(=CC(=C5N=C4CC)C)C)C(F)(F)F
Molecular Formula
C27H24F3N5O2S
Molecular Weight
539.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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