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Duocarmycin GA

CAT: 0931-T11115-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T11115-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1613286-59-1
Target
ADC Cytotoxin, DNA Alkylator/Crosslinker
Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Bioactivity
Duocarmycin GA, an antibody drug conjugate (ADC) toxin and a DNA alkylating agent, effectively targets and binds in the minor groove of DNA. It is particularly potent against multi-drug resistant cell lines, offering a strategic approach in combating resistance.
Smiles
C(Cl)[C@H]1C2=C(N(C(=O)C=3NC=4C(C3)=CC=C(NC(CN(C)C)=O)C4)C1)C=C(O)C=5C2=CC=CC5
Molecular Formula
C26H25ClN4O3
Molecular Weight
476.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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