Duocarmycin GA

• Target:

  ADC Cytotoxin|||DNA Alkylator/Crosslinker

• Related Pathways:

  Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair

• Bioactivity:

  Duocarmycin GA, an antibody drug conjugate (ADC) toxin and a DNA alkylating agent, effectively targets and binds in the minor groove of DNA. It is particularly potent against multi-drug resistant cell lines, offering a strategic approach in combating resistance.

• Smiles:

  C(Cl)[C@H]1C2=C(N(C(=O)C=3NC=4C(C3)=CC=C(NC(CN(C)C)=O)C4)C1)C=C(O)C=5C2=CC=CC5

• Molecular Formula:

  C26H25ClN4O3

• Molecular Weight:

  476.96

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1613286-59-1