PROTAC EED degrader-2
CAT:
804-HY-130615-04
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PROTAC EED degrader-2
- CAS Number: 2639882-69-0
- UNSPSC Description: PROTAC EED degrader-2 is a von Hippel-Lindau-based PROTAC targeting EED with a pKD of 9.27. PROTAC EED degrader-2 is a polycomb repressive complex 2 (PRC2) inhibitor (pIC50=8.11) targeting the EED subunit[1].
- Target Antigen: Histone Methyltransferase; PROTACs
- Type: Reference compound
- Related Pathways: Epigenetics;PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/protac-eed-degrader-2.html
- Purity: 99.90
- Solubility: DMSO : 80 mg/mL (ultrasonic)
- Smiles: FC1=CC=C2C(CCO2)=C1CNC3=NC=C(C4=NN=CN34)C5=C(N=C(C=C5)CCC(NCCCCC(N[C@H](C(N6[C@@H](C[C@H](C6)O)C(NCC7=CC=C(C=C7)C8=C(N=CS8)C)=O)=O)C(C)(C)C)=O)=O)C
- Molecular Weight: 960.13
- References & Citations: [1]Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light)
- Clinical Information: No Development Reported