PROTAC ERR? Degrader-2

• Target:

  Estrogen Receptor/ERR|||PROTACs|||Others

• Related Pathways:

  Endocrinology/Hormones|||PROTAC|||Others

• Bioactivity:

  PROTAC ERR? Degrader-2 is a compound consisting of an MDM2 ligand binding group, a linker, and an estrogen-related receptor alpha (ERR?) binding group. This compound is designed to specifically degrade estrogen-related receptor alpha (ERR?), acting as an ERR? degrader[1].

• Smiles:

  C(=O)(N1[C@]([C@](N=C1C2=C(OC(C)C)C=C(OC)C=C2)(C3=CC=C(Cl)C=C3)[H])(C4=CC=C(Cl)C=C4)[H])N5CC(=O)N(CC(NCCCCCNC(/C(=C/C6=CC(OC)=C(OCC7=C(C(F)(F)F)C=C(C(F)(F)F)C=C7)C=C6)/C#N)=O)=O)CC5

• Molecular Formula:

  C57H55Cl2F6N7O8

• Molecular Weight:

  1150.99

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2306388-85-0