PROTAC PARP1 degrader-2

• CAS Number:

  2923686-62-6

• UNSPSC Description:

  PROTAC PARP1 degrader-2 (Compound 72) is a PROTAC degrader for PARP with a DC50IC50 [1]

• Target Antigen:

  PARP; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-parp1-degrader-2.html

• Smiles:

  O=C(C1=NC(F)=C(N2CCN(CC2)CC3=C(F)C4=C(N=C(C)C(N4)=O)C=C3)C=C1)NC5CCN(CC5)C6=CC7=C(C(N(C8CCC(NC8=O)=O)C7=O)=O)C=C6

• Molecular Weight:

  753.75

• References & Citations:

  [1]Li Y, et al., Parp-1 degradation agent and use thereof. WO2023066363.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported