12-HETE

• Target:

  Apoptosis

• Related Pathways:

  Apoptosis

• Bioactivity:

  12-HETE ((±) 12-HETE) is a modulator of PGE2, with both anti-thrombotic and pro-thrombotic effects, inducing PGE2 release and COX-2 expression via phospholipase A2 (sPLA2-IIA) inducers. It is also a neuroregulator activating retinal cell endothelial dysfunction in diabetic retinopathy.

• Smiles:

  C(\C(C/C=C\CCCCC)O)=C/C=C\C/C=C\CCCC(O)=O

• Molecular Formula:

  C20H32O3

• Molecular Weight:

  320.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  71030-37-0