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12 (S) -HETE

CAT: 0931-T37047-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0931-T37047-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
54397-83-0
Target
DNA/RNA Synthesis, p38 MAPK, ERK
Related Pathways
DNA Damage/DNA Repair, MAPK, Cell Cycle/Checkpoint
Bioactivity
12 (S) -HETE, a 12-lipoxygenase metabolite of arachidonic acid, is mitogenic for cancer cell proliferation and enhances angiotensin II-induced contraction of BLT2 (type 2 receptor in arteries of leukotriene B4 mice) and TP (thromboxane receptor) -mediated mechanisms. 12 (S) -HETE promotes superoxide and isothromboxane-like metabolites in arterial endothelial cells. production.
Smiles
C(\[C@H](C/C=C\CCCCC)O)=C/C=C\C/C=C\CCCC(O)=O
Molecular Formula
C20H32O3
Molecular Weight
320.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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