12 (S) -HETE

• Target:

  DNA/RNA Synthesis|||p38 MAPK|||ERK

• Related Pathways:

  DNA Damage/DNA Repair|||MAPK|||Cell Cycle/Checkpoint

• Bioactivity:

  12 (S) -HETE, a 12-lipoxygenase metabolite of arachidonic acid, is mitogenic for cancer cell proliferation and enhances angiotensin II-induced contraction of BLT2 (type 2 receptor in arteries of leukotriene B4 mice) and TP (thromboxane receptor) -mediated mechanisms. 12 (S) -HETE promotes superoxide and isothromboxane-like metabolites in arterial endothelial cells. production.

• Smiles:

  C (\[C@H] (C/C=C\CCCCC) O) =C/C=C\C/C=C\CCCC (O) =O

• Molecular Formula:

  C20H32O3

• Molecular Weight:

  320.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  54397-83-0