12 (S) -HETE

• Target :

  DNA/RNA Synthesis|||p38 MAPK|||ERK

• Related Pathways :

  DNA Damage/DNA Repair|||MAPK|||Cell Cycle/Checkpoint

• Bioactivity :

  12 (S) -HETE, a 12-lipoxygenase metabolite of arachidonic acid, is mitogenic for cancer cell proliferation and enhances angiotensin II-induced contraction of BLT2 (type 2 receptor in arteries of leukotriene B4 mice) and TP (thromboxane receptor) -mediated mechanisms. 12 (S) -HETE promotes superoxide and isothromboxane-like metabolites in arterial endothelial cells. production.

• Smiles :

  C(\[C@H](C/C=C\CCCCC)O)=C/C=C\C/C=C\CCCC(O)=O

• Molecular Formula :

  C20H32O3

• Molecular Weight :

  320.47

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  54397-83-0