(±) 17-HETE

CAT: 0931-T35523-01Size: 25 µgDry Ice: NoHazardous: No
CAT#:0931-T35523-01Size:25 µg
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CAS Number
128914-47-6
Target
Others|||ATPase|||Cytochromes P450
Related Pathways
Metabolism|||Membrane transporter/Ion channel|||Others
Bioactivity
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±) 17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 ?M the (S) -enantiomer of 17-HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R) -isomer is inactive.
Smiles
CCCC(O)C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
Molecular Formula
C20H32O3
Molecular Weight
320.473
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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