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12 (R) -HETE

CAT: 0931-T36145-01Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0931-T36145-01Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
82337-46-0
Target
Others, Aryl Hydrocarbon Receptor, ATPase
Related Pathways
Immunology/Inflammation, Membrane transporter/Ion channel, Others
Bioactivity
Biosynthesis of 12 (R) -HETE in invertebrates is via lipoxygenation of arachidonic acid . In mammals, 12 (R) -HETE can be produced by 12 (R) -LOs and also by CYP450 oxidation. The activity of 12 (R) -HETE in mammals is predominantly proinflammatory. 12 (R) -HETE exhibits dose-dependent leukocyte chemotaxis at concentrations as low as 100 nM, and lowers intraocular pressure in rabbits.
Smiles
C(\[C@@H](C/C=C\CCCCC)O)=C/C=C\C/C=C\CCCC(O)=O
Molecular Formula
C20H32O3
Molecular Weight
320.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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