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SKLB 1028

CAT: 0931-T34656-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T34656-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1350544-93-2
Target
EGFR, FLT, Bcr-Abl
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Cytoskeletal Signaling
Purity
0.9999
Bioactivity
SKLB 1028 (Ruserontinib) is a new type of oral multikinase inhibitor of EGFR, FLT3, and Abl. SKLB 1028 shows excellent activity in FLT3-driven AML models and considerable potency in CML models containing Abl mutants.
Smiles
C(C)(C)N1C=2C(N=C1NC=3C=CC=NC3)=CN=C(NC4=CC=C(C=C4)N5CCN(C)CC5)N2
Molecular Formula
C24H29N9
Molecular Weight
443.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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