SKLB 1028

• CAS Number :

  1350544-93-2

• Target :

  EGFR|||FLT|||Bcr-Abl

• Related Pathways :

  JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Cytoskeletal Signaling

• Purity :

  0.9999

• Bioactivity :

  SKLB 1028 (Ruserontinib) is a new type of oral multikinase inhibitor of EGFR, FLT3, and Abl. SKLB 1028 shows excellent activity in FLT3-driven AML models and considerable potency in CML models containing Abl mutants.

• Smiles :

  C(C)(C)N1C=2C(N=C1NC=3C=CC=NC3)=CN=C(NC4=CC=C(C=C4)N5CCN(C)CC5)N2

• Molecular Formula :

  C24H29N9

• Molecular Weight :

  443.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C