SKLB 1028

• Target:

  EGFR|||FLT|||Bcr-Abl

• Related Pathways:

  JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Cytoskeletal Signaling

• Purity:

  0.9999

• Bioactivity:

  SKLB 1028 (Ruserontinib) is a new type of oral multikinase inhibitor of EGFR, FLT3, and Abl. SKLB 1028 shows excellent activity in FLT3-driven AML models and considerable potency in CML models containing Abl mutants.

• Smiles:

  C (C) (C) N1C=2C (N=C1NC=3C=CC=NC3) =CN=C (NC4=CC=C (C=C4) N5CCN (C) CC5) N2

• Molecular Formula:

  C24H29N9

• Molecular Weight:

  443.55

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1350544-93-2