SKLB 610

• Target:

  PDGFR|||VEGFR|||FGFR

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity:

  0.9983

• Bioactivity:

  SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively, at the concentration of 10 ?M in biochemical kinase assays.

• Smiles:

  O (C=1C=C (C (NC) =O) N=CC1) C2=CC=C (NC (=O) C3=CC (C (F) (F) F) =CC=C3) C=C2

• Molecular Formula:

  C21H16F3N3O3

• Molecular Weight:

  415.37

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1125780-41-7