SKLB-11A

• Target :

  Autophagy|||Sirtuin

• Related Pathways :

  DNA Damage/DNA Repair|||Autophagy|||Chromatin/Epigenetic

• Bioactivity :

  SKLB-11A is a potent allosteric agonist of SIRT3 (sirtuin 3) . It activates signaling pathways associated with autophagy (autophagy), helps prevent mitochondrial dysfunction, and improves cardiac function in models of Doxorubicin-induced cardiotoxicity as well as myocardial ischemia/reperfusion.

• Smiles :

  O=C(OC)C=1C=2N=C3C=CC=CC3=NC2N(C1N)CC4=CC=C(F)C=C4

• Molecular Formula :

  C19H15FN4O2

• Molecular Weight :

  350.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  433953-86-7