SKLB-197

CAT: 0931-T62290-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T62290-01Size:25 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
2713577-16-1
Target
Others|||ATM/ATR
Related Pathways
Others|||PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair
Bioactivity
SKLB-197 is able to act on ATR (IC50: 0.013 ?M), but has little or no activity on the other 402 protein kinases. In vitro and in vivo, SKLB-197 has shown significant antitumour effects against ATM-deficient tumours.
Smiles
C[C@@H]1COCCN1c1nc(nc2ccc(cc12)-c1ccnn1C)-c1cccc2[nH]ccc12
Molecular Formula
C25H24N6O
Molecular Weight
424.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Popular Products