AMG-337

• Target:

  C-Met/HGFR|||Caspase|||Apoptosis

• Related Pathways:

  Proteases/Proteasome|||Tyrosine Kinase/Adaptors|||Apoptosis

• Purity:

  0.999

• Bioactivity:

  AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337 (AMG337) inhibits MET kinase activity (IC50: < 5 nM) .

• Smiles:

  COCCOc1cnc2ccn([C@H](C)c3nnc4c(F)cc(cn34)-c3cnn(C)c3)c(=O)c2c1

• Molecular Formula:

  C23H22FN7O3

• Molecular Weight:

  463.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1173699-31-4