CS-003 Free base

• Target:

  Neurokinin receptor

• Related Pathways:

  GPCR/G Protein|||Neuroscience

• Bioactivity:

  CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3 nM and 0.54 nM, respectively And 0.74 nM. CS-003 free base (CS-003) has therapeutic effects on neurokinin-related respiratory diseases.

• Smiles:

  O=S1C2(C=3C(C1)=CC=CC3)CCN(CC[C@]4(CN(C(=O)C5=CC(OC)=C(OC)C(OC)=C5)CCO4)C6=CC(Cl)=C(Cl)C=C6)CC2

• Molecular Formula:

  C34H38Cl2N2O6S

• Molecular Weight:

  673.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  191672-52-3