CS-722 (Free base)

• Description :

  CS-722 Free base is a synthesized centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex[1]. CS-722 Free base inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents[2].

• CAS Number :

  [749179-13-3]

• UNSPSC :

  12352005

• Target :

  Endogenous Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/cs-722-free-base.html

• Solubility :

  10 mM in DMSO

• Smiles :

  ClC1=C(C2=CC=CC=C2)ON(C[C@H](O)CN3CCOCC3)C1=O

• Molecular Formula :

  C16H19ClN2O4

• Molecular Weight :

  338.79

• References & Citations :

  [1]Tanabe M, et al. Preferential enhancement of inhibitory synaptic transmission by CS-722 in the ventral horn neurons of neonatal rat spinal cord. Eur J Pharmacol. 1996 Oct 17;313 (3) :187-9.|[2]Marszalec W, et al. The effects of the muscle relaxant, CS-722, on synaptic activity of cultured neurones. Br J Pharmacol. 1996 Sep;119 (1) :126-32.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported