CS-722 (Free base)

CS-722 (Free base)

• CAS Number: 749179-13-3
• UNSPSC Description: CS-722 Free base is a synthesized centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex[1]. CS-722 Free base inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents[2].
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/cs-722-free-base.html
• Solubility: 10 mM in DMSO
• Smiles: ClC1=C(C2=CC=CC=C2)ON(C[C@H](O)CN3CCOCC3)C1=O
• Molecular Weight: 338.79
• References & Citations: [1]Tanabe M, et al. Preferential enhancement of inhibitory synaptic transmission by CS-722 in the ventral horn neurons of neonatal rat spinal cord. Eur J Pharmacol. 1996 Oct 17;313(3):187-9.|[2]Marszalec W, et al. The effects of the muscle relaxant, CS-722, on synaptic activity of cultured neurones. Br J Pharmacol. 1996 Sep;119(1):126-32.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported