Products for Research Use Only
RegisterLogin

DX3-213B

CAT: 0804-HY-144310-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-144310-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DX3-213B is a highly potent, orally active oxidative phosphorylation (OXPHOS) complex I inhibitor (IC50=3.6 nM) . DX3-213B impairs ATP generation (IC50=11 nM), and blocks MIA PaCa-2 cell growth (GI50=11 nM) . DX3-213B is used for the research of the pancreatic cancer[1].
CAS Number
2749555-66-4
UNSPSC
12352005
Target
Mitochondrial Metabolism; Oxidative Phosphorylation
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dx3-213b.html
Concentration
10mM
Purity
99.68
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(N1C[C@@H](CCC1)C(N2CCC(F)(CC2)F)=O)(C3=CC=C(C=C3)S(C(C)C)(=O)=O)=O
Molecular Formula
C20H28F2N2O5S2
Molecular Weight
478.57
References & Citations
[1]Xue D, et al. Multiparameter Optimization of Oxidative Phosphorylation Inhibitors for the Treatment of Pancreatic Cancer. J Med Chem. 2022;65 (4) :3404-3419.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-145306-01DX3-234
HY-145304-01DX3-235
HY-12369-01GGTI-2133
HY-161162-01ATAG 2139
HY-169138-01ZD 2138
HY-164906TMX-2138
HY-123646RS 2135
HY-12369AGGTI-2133 (TFA)
HY-161161-01ATAG 2139-NEG
HY-165272Antibiotic SF-2132

Alternative Products

CatalogName
BA7997-5DX3-213B
ABC-TC0228DX3
T64108-01DX3-235
T64004-01DX3-234
99-588CD95 Antibody [DX3]
99-585CD95 Antibody [DX3] (PE)

Popular Products