DX3-234

• Description:

  DX3-234 is an oxidative phosphorylation (OXPHOS) inhibitor. DX3-234 shows significant tumor suppression in the Pan02 syngeneic model of pancreatic cancer[1].

• UNSPSC:

  12352005

• Target:

  Mitochondrial Metabolism; Oxidative Phosphorylation

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dx3-234.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S(C1=CC=C(C=C1)S(=O)(N2C[C@@H](CCC2)C(N3CCN(CC3)C4=NC(C(C)C)=NO4)=O)=O)(C5CCC5)=O

• Molecular Formula:

  C25H35N5O6S2

• Molecular Weight:

  565.71

• References & Citations:

  [1]Xue D, et al. Discovery and Lead Optimization of Benzene-1,4-disulfonamides as Oxidative Phosphorylation Inhibitors. J Med Chem. 2022;65 (1) :343-368.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2941323-59-5