DX3-234

• Target:

  OXPHOS|||Mitochondrial Metabolism

• Related Pathways:

  Apoptosis|||Metabolism

• Purity:

  0.993

• Bioactivity:

  DX3-234 is a potent oxidative phosphorylation (OXPHOS) inhibitor that acts by inhibiting complex I in the mitochondrial electron transport chain (ETC), leading to intracellular ATP depletion and cell death, and can be used for the treatment of specific cancers dependent on aerobic metabolism, such as pancreatic cancer.

• Smiles:

  C(C)(C)C=1N=C(ON1)N2CCN(C(=O)[C@H]3CN(S(=O)(=O)C4=CC=C(S(=O)(=O)C5CCC5)C=C4)CCC3)CC2

• Molecular Formula:

  C25H35N5O6S2

• Molecular Weight:

  565.71

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2941323-59-5