ATAG 2139-NEG

• Description :

  ATAG 2139-NEG (Compound 23) binds to MTH1 and has no degradative activity with a Ki value of 2.0 nM. aTAG 2139-NEG serves as aTAG 2139 negative control[1].

• UNSPSC :

  12352005

• Target :

  DNA/RNA Synthesis

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/atag-2139-neg.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC=C(C2=CC=C3N=CC(C(NC)=O)=C(C3=C2)NC4=CC=CC=C4)C=N1)NCCCCNC(COC5=CC=CC(C(N6C7C(N(C)C(CC7)=O)=O)=O)=C5C6=O)=O

• Molecular Formula :

  C43H40N8O8

• Molecular Weight :

  796.83

• References & Citations :

  [1]Veits G K, et al. Development of an AchillesTAG degradation system and its application to control CAR-T activity[J]. Current Research in Chemical Biology, 2021, 1: 100010.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2758431-99-9]