GGTI-2133 (TFA)

• UNSPSC Description:

  GGTI-2133 TFA is the TFA salt form of GGTI-2133 (HY-12369). GGTI-2133 TFA is an inhibitor for geranylgeranyltransferase I (GGTase-I) with an IC50 of 38 nM. GGTI-2133 TFA inhibits the geranylation of Rap-1A with an IC50 of 10 μM[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ggti-2133-tfa.html

• Smiles:

  CC(C)C[C@@H](C(O)=O)NC(C1=CC=C(NCC2=CN=CN2)C=C1C3=C4C=CC=CC4=CC=C3)=O.O=C(O)C(F)(F)F

• Molecular Weight:

  570.56

• References & Citations:

  [1]Vasudevan A, et al., Potent, highly selective, and non-thiol inhibitors of protein geranylgeranyltransferase-I. J Med Chem. 1999 Apr 22;42(8):1333-40.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1217480-14-2