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ATAG 2139

CAT: 0804-HY-161162-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-161162-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ATAG 2139 (CFT-2139) is an aTAG-based MTH1 fusion protein degrader with a DC50 value of 1.1 nM. aTAG 2139 has a Ki value of 2.1 nM for MTH1[1].
CAS Number
2387510-81-6
Product Name Alternative
CFT-2139
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/atag-2139.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C2=CC=C3N=CC(C(NC)=O)=C(C3=C2)NC4=CC=CC=C4)C=N1)NCCCCNC(COC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)=O
Molecular Formula
C42H38N8O8
Molecular Weight
782.80
References & Citations
[1]Veits G K, et al. Development of an AchillesTAG degradation system and its application to control CAR-T activity[J]. Current Research in Chemical Biology, 2021, 1: 100010.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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