CPD-39

• UNSPSC Description:

  CPD-39 is a potent and orally active CCND1 and CDK4 heterobifunctional PROTAC degrader. CPD-39 shows anti-proliferation. (Pink: ligand for target protein (HY-50767); black: linker (HY-20240); Blue: E3 ligase ligand (HY-168667))[1].

• Target Antigen:

  CDK; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;PROTAC

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cpd-39.html

• Smiles:

  CC(C1=C(C2=C(N(C1=O)C3CCCC3)N=C(N=C2)NC4=CC=C(C=N4)N5CCN(CC5)CC(NC6CC7(CC(C7)NC8=NC(NC)=CC=C8C(NC9=NN=C(C=C9)N(C)C)=O)C6)=O)C)=O

• Molecular Weight:

  884.04

• References & Citations:

  [1]Jing Liu, et al. Compounds and methods of treating cancers. French, WO2024183798A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3055472-38-0