CPD-39

CAT: 0804-HY-168664-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-168664-01Size:5 mg
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Description
CPD-39 is a potent and orally active CCND1 and CDK4 heterobifunctional PROTAC degrader. CPD-39 shows anti-proliferation. (Pink: ligand for target protein (HY-50767) ; black: linker (HY-20240) ; Blue: E3 ligase ligand (HY-168667) ) [1].
CAS Number
[3055472-38-0]
UNSPSC
12352211
Target
CDK; PROTACs
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cpd-39.html
Purity
98.06
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=C(C2=C(N(C1=O)C3CCCC3)N=C(N=C2)NC4=CC=C(C=N4)N5CCN(CC5)CC(NC6CC7(CC(C7)NC8=NC(NC)=CC=C8C(NC9=NN=C(C=C9)N(C)C)=O)C6)=O)C)=O
Molecular Formula
C46H57N15O4
Molecular Weight
884.04
References & Citations
[1]Jing Liu, et al. Compounds and methods of treating cancers. French, WO2024183798A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK4

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