CM-39

• Description :

  CM-39 is a non-covalent and reversible inhibitor for aldehyde dehydrogenase 1A (ALDH1A) with an IC50 of 0.9 μM[1].

• CAS Number :

  [361156-54-9]

• UNSPSC :

  12352005

• Target :

  Aldehyde Dehydrogenase (ALDH)

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cm-39.html

• Smiles :

  O=C1C2=C(NN=C2)N=C(SCC3=CC=CC(F)=C3)N1C4=CC=CC=C4C

• Molecular Formula :

  C19H15FN4OS

• Molecular Weight :

  366.41

• References & Citations :

  [1]Huddle BC, et al., Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy. J Med Chem. 2018 Oct 11;61 (19) :8754-8773.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  ALDH1