CM-39

CAT: 0804-HY-129314Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-129314Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CM-39 is a non-covalent and reversible inhibitor for aldehyde dehydrogenase 1A (ALDH1A) with an IC50 of 0.9 μM[1].
CAS Number
[361156-54-9]
UNSPSC
12352005
Target
Aldehyde Dehydrogenase (ALDH)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cm-39.html
Smiles
O=C1C2=C(NN=C2)N=C(SCC3=CC=CC(F)=C3)N1C4=CC=CC=C4C
Molecular Formula
C19H15FN4OS
Molecular Weight
366.41
References & Citations
[1]Huddle BC, et al., Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy. J Med Chem. 2018 Oct 11;61 (19) :8754-8773.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ALDH1

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