CM-39

• UNSPSC Description:

  CM-39 is a non-covalent and reversible inhibitor for aldehyde dehydrogenase 1A (ALDH1A) with an IC50 of 0.9 μM[1].

• Target Antigen:

  Aldehyde Dehydrogenase (ALDH)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cm-39.html

• Smiles:

  O=C1C2=C(NN=C2)N=C(SCC3=CC=CC(F)=C3)N1C4=CC=CC=C4C

• Molecular Weight:

  366.41

• References & Citations:

  [1]Huddle BC, et al., Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy. J Med Chem. 2018 Oct 11;61(19):8754-8773.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  361156-54-9