AChE-IN-39

• Description :

  AChE-IN-39 (Compound 7c) is an AChE inhibitor (IC50: 0.058 μM) . AChE-IN-39 has DPPH scavenging activity. AChE-IN-39 improves the cognitive impairment in AlCl3-induced amnesia animal model. AChE-IN-39 can be used for research of Alzheimer's disease[1].

• UNSPSC :

  12352005

• Target :

  Cholinesterase (ChE)

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ache-in-39.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC2=C(C=CC=C2)O1)/C=C/NC3=CC(C(C)=O)=CC=C3

• Molecular Formula :

  C19H15NO3

• Molecular Weight :

  305.33

• References & Citations :

  [1]Somaia S. Abd El-Karim, et al. Discovery of novel benzofuran-based derivatives as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease: Design, synthesis, biological evaluation, molecular docking and 3D-QSAR investigation. European Journal of Medicinal Chemistry. 2013, 115766.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported