CPD-2828

CAT: 0804-HY-174991Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-174991Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CPD-2828 is an orally active and selective IRE1α inhibitor with an IC50 value of 1.2 μM. CPD-2828 is promising for research of endoplasmic reticulum stress-related diseases (e.g., cancer, neurodegenerative diseases) [1].
UNSPSC
12352005
Target
IRE1
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer; Neurological Disease
Smiles
O=CC1=C(O)C=CC2=C1OC(C(CC(N3CCC(C4=CC=C(NC(CC5)C(NC5=O)=O)C=C4)CC3)=O)=C2C)=O
Molecular Formula
C29H29N3O7
Molecular Weight
531.56
References & Citations
[1]Zerfas BL, et al. Structure-guided design of a truncated heterobivalent chemical probe degrader of IRE1α. RSC Med Chem. 2025 Mar 18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IRE1α

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