CPD-1224

• Target :

  Others|||ALK

• Related Pathways :

  Others|||Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity :

  CPD-1224, an orally active derivative that binds cereblon ligands to ALK inhibitors, specifically targets and degrades EML4-ALK oncogenic fusions, including ALK and its mutants L1196M/G1202R.

• Smiles :

  O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CC(C4)CN5CCC(C6=CC(OC)=C(C=C6C)NC7=NC=C(Cl)C(=N7)NC=8C=CC=CC8S(=O)(=O)C(C)C)CC5

• Molecular Formula :

  C43H47ClN8O7S

• Molecular Weight :

  855.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2891620-68-9