CJ-463

• Description:

  CJ-463 is a potent and selective uPA inhibitor. CJ-463 has antitumor activity[1].

• UNSPSC:

  12352005

• Target:

  PAI-1

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cj-463.html

• Smiles:

  N=C(N)C1=CC=C(C=C1)CNC([C@H](CO)NC([C@H](NS(=O)(CC2=CC=CC=C2)=O)CO)=O)=O

• Molecular Formula:

  C21H27N5O6S

• Molecular Weight:

  477.53

• References & Citations:

  [1]Henneke I, et al. Inhibition of urokinase activity reduces primary tumor growth and metastasis formation in a murine lung carcinoma model. Am J Respir Crit Care Med. 2010 Mar 15;181 (6) :611-9.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  600142-19-6