CJ-15208

• Target:

  Others|||Opioid Receptor

• Related Pathways:

  Endocrinology/Hormones|||Neuroscience|||GPCR/G Protein|||Others

• Bioactivity:

  CJ-15208 is a potent and selective ?-opioid receptor antagonist from a fungus, Ctenomyces serratus ATCC15502 (IC50 are 47 nM for kappa, 260 nM for mu, and 2,600 nM for delta respectly) . In the electrically-stimulated twitch response assay of rabbit vas deferens, CJ-15208 recovered the suppression by a kappa agonist asimadoline with an ED50 of 1.3 microM.

• Smiles:

  C (C=1C=2C (NC1) =CC=CC2) [C@H]3C (=O) N[C@@H] (CC4=CC=CC=C4) C (=O) N5[C@@] (C (=O) N[C@@H] (CC6=CC=CC=C6) C (=O) N3) (CCC5) [H]

• Molecular Formula:

  C34H35N5O4

• Molecular Weight:

  577.67

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  210236-47-8