CJ-42794

• Target:

  Others|||Prostaglandin Receptor

• Related Pathways:

  GPCR/G Protein|||Immunology/Inflammation|||Others

• Purity:

  0.9992

• Bioactivity:

  CJ-42794 (CJ-042794) is a selective antagonist of the prostaglandin E receptor subtype 4 (EP4), inhibiting [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5. It exhibits a binding affinity that is at least 200-fold more selective for the human EP4 receptor than for other human EP receptor subtypes (EP1, EP2, and EP3) (IC50: 8.5 (pKi) ) .

• Smiles:

  C[C@H](NC(=O)c1cc(Cl)ccc1Oc1ccc(F)cc1)c1ccc(cc1)C(O)=O

• Molecular Formula:

  C22H17ClFNO4

• Molecular Weight:

  413.83

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  847728-01-2