CJ-463

• Target:

  PAI-1|||Others

• Related Pathways:

  Others|||Metabolism

• Bioactivity:

  CJ-463 is a potent ans selective uPA inhibitor. Treatment with CJ-463 resulted in a significant inhibition of primary tumor growth, with the highest efficacy seen in the 100 mg/kg group. Urokinase (uPA) plays a crucial role in carcinogenesis by facilitating tumor cell invasion and metastasis. CJ-463 may be a novel agent for treatment of lung cancer.

• Smiles:

  C(NC([C@@H](NC([C@H](NS(CC1=CC=CC=C1)(=O)=O)CO)=O)CO)=O)C2=CC=C(C(=N)N)C=C2

• Molecular Formula:

  C21H27N5O6S

• Molecular Weight:

  477.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  600142-19-6